Main clinical applications of parametric cardiac magnetic resonance mapping techniques
DOI:
https://doi.org/10.37615/retic.v8n2a2Keywords:
mapping, magnetic resonance, cardiomyopathyAbstract
Parametric mapping techniques provide a non-invasive tool for quantifying tissue alterations in various cardiac pathologies. They measure changes in myocardial composition based on T1, T2, and T2* (star) relaxation times and extracellular volume. These techniques focus on specific pathological pathways, which are primarily related to intracellular alterations in the cardiomyocyte and/or extracellular alterations in the myocardial interstitium. This improves the diagnosis, risk stratification, follow-up and assessment of treatment response for various types of cardiomyopathies.
This article shows the main clinical scenarios in which these parametric techniques are applied.
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Messroghli DR, Moon JC, Ferreira VM, et al. Clinical recommendations for cardiovascular magnetic resonance mapping of T1, T2 T2* and extracellular volume: A consensus statement by the Society for Cardiovascular Magnetic Resonance (SCMR) endorsed by the European Association for Cardiovascular Imaging (EACVI). J Cardiovascular Magn Reson (2017); 19 (1):75. DOI: https://doi.org/10.1186/s12968-017-0389-8
Haaf P, Garg P, Messroghli DR, Broadbent DA, et al. Cardiac T1 Mapping and Extracellular Volume (ECV) in clinical practice: comprehensive review. J Cardiovasc Magn Reson. 2016;18(1):89. DOI: https://doi.org/10.1186/s12968-016-0308-4
Captur G, Manisty C, Moon JC. Cardiac MRI evaluation of myocardial disease. Heart. 2016;102(18):1429–35. DOI: https://doi.org/10.1136/heartjnl-2015-309077
Lewis AJM, Burrage MK, Ferreira VM. Cardiovascular magnetic resonance imaging for inflammatory heart diseases. Cardiovasc Diagn Ther. 2020; 10(3): 598-609. DOI: https://doi.org/10.21037/cdt.2019.12.09
Ferreira VM, Schulz-Menger J, Holmvang G, Kramer cm, Carbone I, Sechtem U, et al. Cardiovascular magnetic resonance in nonischemic myocardial inflammation: Expert recommendations. J am Coll Cardiol. 2018; 72 (24)3158-76. DOI: https://doi.org/10.1016/j.jacc.2018.09.072
Ntusi NAB, Piecnik SK, Francis JM et al. Diffuse myocardial fibrosis and inflammation in rheumatoid arthritis: Insights from CMR T1 mapping. JACC Cardiovasc Imaging 2015;8(5):526-36. DOI: https://doi.org/10.1016/j.jcmg.2014.12.025
Guo Q, Wu L-M, Wang Z, et al. Early detection of silent myocardial impairment in patients with new onset drug-naive systemic lupus erythematosus. A three-center prospective study (myocardial impairment in new onset SLE): A three- center prospective study. Arthritis Rheumatol 2018;70(12):2014-24. DOI: https://doi.org/10.1002/art.40671
Argentiero A, Carella MC, Mandunzio D, et al. Cardiac magnetic resonance as risk stratification tool in non- ischemic dilated cardiomyopathy referred for implantable cardioverter defibrillator therapy – state of art and perspectives. J Clin Med 2023;12(24):7752. DOI: https://doi.org/10.3390/jcm12247752
Pan JA, Kerwin MJ, Salerno M. Native T1 mapping, extracellular volume mapping, and late gadolinium enhancement in cardiac amyloidosis: A meta-analysis. JACC Cardiovasc Imaging 2020;13(6):1299–310. DOI: https://doi.org/10.1016/j.jcmg.2020.03.010
Cai S, Haghbayan H, Chan KKW, et al. Tissue mapping by cardiac magnetic resonance imaging for the prognostication of cardiac amyloidosis: A systematic review and meta-analysis. Int J Cardiol 2024;403(131892):131892. DOI: https://doi.org/10.1016/j.ijcard.2024.131892
Ponsiglione A, Gambardella M, Green R, et al. Cardiovascular magnetic resonance native T1 mapping in Anderson-Fabry disease: a systematic review and meta-analysis. J Cardiovasc Magn Reson 2022;24(1):31. DOI: https://doi.org/10.1186/s12968-022-00859-z
Sado DM, White SK, Piechnik SK, et al. Identification and assessment of Anderson-Fabry disease by cardiovascular magnetic resonance noncontract myocardial T1 mapping. Circ Cardiovasc Imaging. 2013;6(3):392–8. DOI: https://doi.org/10.1161/CIRCIMAGING.112.000070
Swoboda PP, McDiarmid AK, Erhayiem B, et al. Assessing myocardial extracellular volume by T1 mapping to distinguish hypertrophic cardiomyopathy from athlete’s heart. J Am Coll Cardiol. 2016;67(18):2189–90. DOI: https://doi.org/10.1016/j.jacc.2016.02.054
Plana JC, Thavendiranathan P, Bucciarelli-Ducci C, Lancellotti P. Multi-modality imaging in the assessment of cardiovascular toxicity in the cancer patient. JACC Cardiovasc Imaging 2018;11(8):1173–86. DOI: https://doi.org/10.1016/j.jcmg.2018.06.003
Lisi C, Catapano F, Rondi P, et al. Multimodality imaging in cardio-oncology: the added value of CMR and CCTA. Br J Radiol 2023;96(1150):20220999. DOI: https://doi.org/10.1259/bjr.20220999
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Copyright (c) 2025 Natalia Cobo Gómez, Jordi Broncano Cabrero, Gabriela Muller Bravo, Antonio Luna Alcalá

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